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Insights on the mutational landscape of the SARS-CoV-2 Omicron variant receptor-binding domain

The Omicron variant features enhanced transmissibility and antibody escape. Here, we describe the Omicron receptor-binding domain (RBD) mutational landscape using amino acid interaction (AAI) networks, which are well suited for interrogating constellations of mutations that function in an epistatic...

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Detalles Bibliográficos
Autores principales: Miller, Nathaniel L., Clark, Thomas, Raman, Rahul, Sasisekharan, Ram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784435/
https://www.ncbi.nlm.nih.gov/pubmed/35233548
http://dx.doi.org/10.1016/j.xcrm.2022.100527