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Tetrahydrobiopterin Administration Augments Exercise-Induced Hyperemia and Endothelial Function in Patients With Systemic Sclerosis

Systemic sclerosis (SSc) is a rare, auto-immune disease with variably progressive fibrosis of the skin and internal organs, as well as vascular dysfunction. Recently, we demonstrated a decrement in exercising skeletal muscle blood flow and endothelium-dependent vasodilation in SSc, but the mechanism...

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Detalles Bibliográficos
Autores principales: Machin, Daniel R., Clifton, Heather L., Wray, D. Walter, Frech, Tracy M., Donato, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784551/
https://www.ncbi.nlm.nih.gov/pubmed/35083247
http://dx.doi.org/10.3389/fmed.2021.791689