Cargando…

Tetrahydrobiopterin Administration Augments Exercise-Induced Hyperemia and Endothelial Function in Patients With Systemic Sclerosis

Systemic sclerosis (SSc) is a rare, auto-immune disease with variably progressive fibrosis of the skin and internal organs, as well as vascular dysfunction. Recently, we demonstrated a decrement in exercising skeletal muscle blood flow and endothelium-dependent vasodilation in SSc, but the mechanism...

Descripción completa

Detalles Bibliográficos
Autores principales:	Machin, Daniel R., Clifton, Heather L., Wray, D. Walter, Frech, Tracy M., Donato, Anthony J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784551/ https://www.ncbi.nlm.nih.gov/pubmed/35083247 http://dx.doi.org/10.3389/fmed.2021.791689

Ejemplares similares

Duration of Hyperemia With Intracoronary Administration of Papaverine
por: Mizukami, Takuya, et al.
Publicado: (2021)

Dexamethasone, tetrahydrobiopterin and uncoupling of endothelial nitric oxide synthase
por: Tobias, Silke, et al.
Publicado: (2015)

A key role for tetrahydrobiopterin‐dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin‐deficient mice
por: Chuaiphichai, Surawee, et al.
Publicado: (2017)

Role for Tetrahydrobiopterin in the Fetoplacental Endothelial Dysfunction in Maternal Supraphysiological Hypercholesterolemia
por: Leiva, Andrea, et al.
Publicado: (2016)

A novel role for endothelial tetrahydrobiopterin in mitochondrial redox balance
por: Bailey, Jade, et al.
Publicado: (2017)

Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina
por: Rivera, José Carlos, et al.
Publicado: (2017)

Intracoronary nicorandil induced hyperemia for physiological assessments in the coronary artery lesions
por: Yang, Xia, et al.
Publicado: (2022)

Sympathetic limitation of exercise hyperemia: even hypoperfused muscle is not exempted
por: Duncker, D. J., et al.
Publicado: (2012)

Sustained exercise hyperemia during prolonged adenosine infusion in humans
por: Ranadive, Sushant M., et al.
Publicado: (2019)

M. Andral on Hyperemia
Publicado: (1832)

Tetrahydrobiopterin Improves Endothelial Function in Cardiovascular Disease: A Systematic Review
por: Wang, Qiongying, et al.
Publicado: (2014)

Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression
por: Douglas, Gillian, et al.
Publicado: (2018)

Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension()
por: Chuaiphichai, Surawee, et al.
Publicado: (2016)

Effect of acute hypobaric hypoxia on the endothelial glycocalyx and digital reactive hyperemia in humans
por: Johansson, Pär I., et al.
Publicado: (2014)

The frequency of Raynaud’s phenomenon, very early diagnosis of systemic sclerosis, and systemic sclerosis in a large Veteran Health Administration database
por: Frech, Tracy M., et al.
Publicado: (2021)

0888. Administration of tetrahydrobiopterin (BH4) protects renal microcirculation after ischemia and reperfusion
por: Rahmania, L, et al.
Publicado: (2014)

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency
por: Crabtree, Mark J., et al.
Publicado: (2011)

Contrast-induced Hyperemia as an Alternative to Drug-induced Hyperemia in the Evaluation of the Fractional Flow Reserve in Coronary Lesions
por: Shiode, Nobuo, et al.
Publicado: (2017)

Epidermal growth factor receptors in vascular endothelial cells contribute to functional hyperemia in the brain
por: Ferris, Hannah R., et al.
Publicado: (2023)

Epidermal Growth Factor Receptors in Vascular Endothelial Cells Contribute to Functional Hyperemia in the Brain
por: Ferris, Hannah R., et al.
Publicado: (2023)

The Effect of Periodontal Treatment on the Reactive Hyperemia Index. A 1-Year Follow-Up Pilot Study
por: Donders, H. C. M., et al.
Publicado: (2022)

Hypoxia and Reoxygenation Induce Endothelial Nitric Oxide Synthase Uncoupling in Endothelial Cells through Tetrahydrobiopterin Depletion and S-Glutathionylation
por: De Pascali, Francesco, et al.
Publicado: (2014)

Have we missed that neural vasodilator mechanisms may contribute to exercise hyperemia at onset of voluntary exercise?
por: Matsukawa, Kanji, et al.
Publicado: (2013)

Central Tetrahydrobiopterin Concentration in Neurodevelopmental Disorders
por: Frye, Richard E.
Publicado: (2010)

Modulation of Radiation Response by the Tetrahydrobiopterin Pathway
por: Pathak, Rupak, et al.
Publicado: (2015)

Combined oral administration of L-arginine and tetrahydrobiopterin in a rat model of pulmonary arterial hypertension
por: Schreiber, C., et al.
Publicado: (2017)

Tetrahydrobiopterin Supplementation Improves Endothelial Function But Does Not Alter Aortic Stiffness in Patients With Rheumatoid Arthritis
por: Mäki‐Petäjä, Kaisa M., et al.
Publicado: (2016)

Mast cell tetrahydrobiopterin contributes to itch in mice
por: Zschiebsch, Katja, et al.
Publicado: (2018)

Molecular genetics of phenylketonuria and tetrahydrobiopterin deficiency in Jordan
por: Carducci, Carla, et al.
Publicado: (2020)

Kynurenine and Tetrahydrobiopterin Pathways Crosstalk in Pain Hypersensitivity
por: Staats Pires, Ananda, et al.
Publicado: (2020)

Tetrahydrobiopterin deficiencies: Lesson from clinical experience
por: Bozaci, Ayse Ergul, et al.
Publicado: (2021)

Influencing Factors on the Use of Tetrahydrobiopterin in Patients with Phenylketonuria
por: Gao, Hui
Publicado: (2022)

Skeletal Muscle Hyperemia: A Potential Bridge Between Post-exercise Hypotension and Glucose Regulation
por: Pellinger, Thomas K., et al.
Publicado: (2022)

Variable reactive hyperemia in normotensive strains of rat
por: Heimlich, J. Brett, et al.
Publicado: (2014)

Integrated Redox Sensor and Effector Functions for Tetrahydrobiopterin- and Glutathionylation-dependent Endothelial Nitric-oxide Synthase Uncoupling
por: Crabtree, Mark J., et al.
Publicado: (2013)

Comparison of endothelial function improvement estimated with reactive hyperemia index between ramipril and telmisartan in hypertensive patients
por: Ki, You-Jeong, et al.
Publicado: (2017)

ASL demonstrates higher and more homogenous calf muscle perfusion with post-occlusion hyperemia than with exercise
por: Lopez, David, et al.
Publicado: (2013)

Far-Infrared-Emitting Sericite Board Upregulates Endothelial Nitric Oxide Synthase Activity through Increasing Biosynthesis of Tetrahydrobiopterin in Endothelial Cells
por: Kim, Seonhee, et al.
Publicado: (2019)

Prolonged Low Flow Reduces Reactive Hyperemia and Augments Low Flow Mediated Constriction in the Brachial Artery Independent of the Menstrual Cycle
por: Rakobowchuk, Mark, et al.
Publicado: (2013)

Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblasts
Publicado: (1990)

Cannot write session to /tmp/vufind_sessions/sess_59dl098u44n9l9fuo76cpr1a3q