Engineering Organoids for in vitro Modeling of Phenylketonuria

Phenylketonuria is a recessive genetic disorder of amino-acid metabolism, where impaired phenylalanine hydroxylase function leads to the accumulation of neurotoxic phenylalanine levels in the brain. Severe cognitive and neuronal impairment are observed in untreated/late-diagnosed patients, and even...

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Detalles Bibliográficos
Autores principales: Borges, Alice C., Broersen, Kerensa, Leandro, Paula, Fernandes, Tiago G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784555/
https://www.ncbi.nlm.nih.gov/pubmed/35082602
http://dx.doi.org/10.3389/fnmol.2021.787242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784555/
https://www.ncbi.nlm.nih.gov/pubmed/35082602
http://dx.doi.org/10.3389/fnmol.2021.787242

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