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Soy Intake and Risk of Type 2 Diabetes Among Japanese Men and Women: JACC Study

The evidence on the protective effects of soy foods against type 2 diabetes has been inconsistent. We thought to examine the association between the dietary intakes of soy and the risk of diabetes in a prospective study encompassing 21,925 healthy Japanese men and women aged 40–79 years. A validated...

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Autores principales: Yan, Fangyu, Eshak, Ehab S., Shirai, Kokoro, Dong, Jia-Yi, Muraki, Isao, Tamakoshi, Akiko, Iso, Hiroyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784605/
https://www.ncbi.nlm.nih.gov/pubmed/35083266
http://dx.doi.org/10.3389/fnut.2021.813742
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author Yan, Fangyu
Eshak, Ehab S.
Shirai, Kokoro
Dong, Jia-Yi
Muraki, Isao
Tamakoshi, Akiko
Iso, Hiroyasu
author_facet Yan, Fangyu
Eshak, Ehab S.
Shirai, Kokoro
Dong, Jia-Yi
Muraki, Isao
Tamakoshi, Akiko
Iso, Hiroyasu
author_sort Yan, Fangyu
collection PubMed
description The evidence on the protective effects of soy foods against type 2 diabetes has been inconsistent. We thought to examine the association between the dietary intakes of soy and the risk of diabetes in a prospective study encompassing 21,925 healthy Japanese men and women aged 40–79 years. A validated self-administered food frequency questionnaire determined the intakes of soy, and their associations with risk of type 2 diabetes were evaluated by the logistic regression analysis. During the 5-year follow-up period, we observed 593 new cases of type 2 diabetes (302 in men and 291 in women). There was no association between dietary intakes of soy foods and the risk of type 2 diabetes among men. Whereas among women, higher tofu intake was inversely associated with risk of type 2 diabetes; the multivariable odds ratios (ORs) of type 2 diabetes were 0.92 (95% CI: 0.69–1.21) for 3–4 times per week and 0.67 (95% CI: 0.49–0.94) for almost daily (p-trend = 0.03) in reference to those consuming tofu less than 3 times per week. Intakes of boiled beans and miso soup were not associated with the risk in both genders. The inverse association tended to be more evident among overweight women and postmenopaused women. In conclusion, the frequency of tofu intake was inversely associated with the risk of type 2 diabetes among women.
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spelling pubmed-87846052022-01-25 Soy Intake and Risk of Type 2 Diabetes Among Japanese Men and Women: JACC Study Yan, Fangyu Eshak, Ehab S. Shirai, Kokoro Dong, Jia-Yi Muraki, Isao Tamakoshi, Akiko Iso, Hiroyasu Front Nutr Nutrition The evidence on the protective effects of soy foods against type 2 diabetes has been inconsistent. We thought to examine the association between the dietary intakes of soy and the risk of diabetes in a prospective study encompassing 21,925 healthy Japanese men and women aged 40–79 years. A validated self-administered food frequency questionnaire determined the intakes of soy, and their associations with risk of type 2 diabetes were evaluated by the logistic regression analysis. During the 5-year follow-up period, we observed 593 new cases of type 2 diabetes (302 in men and 291 in women). There was no association between dietary intakes of soy foods and the risk of type 2 diabetes among men. Whereas among women, higher tofu intake was inversely associated with risk of type 2 diabetes; the multivariable odds ratios (ORs) of type 2 diabetes were 0.92 (95% CI: 0.69–1.21) for 3–4 times per week and 0.67 (95% CI: 0.49–0.94) for almost daily (p-trend = 0.03) in reference to those consuming tofu less than 3 times per week. Intakes of boiled beans and miso soup were not associated with the risk in both genders. The inverse association tended to be more evident among overweight women and postmenopaused women. In conclusion, the frequency of tofu intake was inversely associated with the risk of type 2 diabetes among women. Frontiers Media S.A. 2022-01-10 /pmc/articles/PMC8784605/ /pubmed/35083266 http://dx.doi.org/10.3389/fnut.2021.813742 Text en Copyright © 2022 Yan, Eshak, Shirai, Dong, Muraki, Tamakoshi and Iso. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Yan, Fangyu
Eshak, Ehab S.
Shirai, Kokoro
Dong, Jia-Yi
Muraki, Isao
Tamakoshi, Akiko
Iso, Hiroyasu
Soy Intake and Risk of Type 2 Diabetes Among Japanese Men and Women: JACC Study
title Soy Intake and Risk of Type 2 Diabetes Among Japanese Men and Women: JACC Study
title_full Soy Intake and Risk of Type 2 Diabetes Among Japanese Men and Women: JACC Study
title_fullStr Soy Intake and Risk of Type 2 Diabetes Among Japanese Men and Women: JACC Study
title_full_unstemmed Soy Intake and Risk of Type 2 Diabetes Among Japanese Men and Women: JACC Study
title_short Soy Intake and Risk of Type 2 Diabetes Among Japanese Men and Women: JACC Study
title_sort soy intake and risk of type 2 diabetes among japanese men and women: jacc study
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784605/
https://www.ncbi.nlm.nih.gov/pubmed/35083266
http://dx.doi.org/10.3389/fnut.2021.813742
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