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mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 omicron variant

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant emerged in November 2021 and consists of several mutations within the spike. We use serum from mRNA-vaccinated individuals to measure neutralization activity against omicron in a live-virus assay. At 2–4 weeks after a p...

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Detalles Bibliográficos
Autores principales: Edara, Venkata-Viswanadh, Manning, Kelly E., Ellis, Madison, Lai, Lilin, Moore, Kathryn M., Foster, Stephanie L., Floyd, Katharine, Davis-Gardner, Meredith E., Mantus, Grace, Nyhoff, Lindsay E., Bechnak, Sarah, Alaaeddine, Ghina, Naji, Amal, Samaha, Hady, Lee, Matthew, Bristow, Laurel, Gagne, Matthew, Roberts-Torres, Jesmine, Henry, Amy R., Godbole, Sucheta, Grakoui, Arash, Saxton, Marybeth, Piantadosi, Anne, Waggoner, Jesse J., Douek, Daniel C., Rouphael, Nadine, Wrammert, Jens, Suthar, Mehul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784612/
https://www.ncbi.nlm.nih.gov/pubmed/35233550
http://dx.doi.org/10.1016/j.xcrm.2022.100529