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Single-Cell Profiles of Age-Related Osteoarthritis Uncover Underlying Heterogeneity Associated With Disease Progression

Objective: Osteoarthritis (OA) is the most common chronic degenerative joint disease, which represents the leading cause of age-related disability. Here, this study aimed to depict the intercellular heterogeneity of OA synovial tissues. Methods: Single-cell RNA sequencing (scRNA-seq) data were prepr...

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Detalles Bibliográficos
Autores principales: Liu, Wenzhou, Chen, Yanbo, Zeng, Gang, Yang, Shuting, Yang, Tao, Ma, Mengjun, Song, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784753/
https://www.ncbi.nlm.nih.gov/pubmed/35083277
http://dx.doi.org/10.3389/fmolb.2021.748360