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Pegylated arginine deiminase drives arginine turnover and systemic autophagy to dictate energy metabolism

Obesity is a multi-systemic disorder of energy balance. Despite intense investigation, the determinants of energy homeostasis remain incompletely understood, and efficacious treatments against obesity and its complications are lacking. Here, we demonstrate that conferred arginine iminohydrolysis by...

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Detalles Bibliográficos
Autores principales: Zhang, Yiming, Higgins, Cassandra B., Van Tine, Brian A., Bomalaski, John S., DeBosch, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784773/
https://www.ncbi.nlm.nih.gov/pubmed/35106510
http://dx.doi.org/10.1016/j.xcrm.2021.100498