Methamphetamine enhances caveolar transport of therapeutic agents across the rodent blood-brain barrier

The blood-brain barrier (BBB) restricts clinically relevant accumulation of many therapeutics in the CNS. Low-dose methamphetamine (METH) induces fluid-phase transcytosis across BBB endothelial cells in vitro and could be used to enhance CNS drug delivery. Here, we show that low-dose METH induces si...

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Detalles Bibliográficos
Autores principales: Chang, Jui-Hsien, Greene, Chris, Frudd, Karen, Araujo dos Santos, Leonardo, Futter, Clare, Nichols, Benjamin J., Campbell, Matthew, Turowski, Patric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784794/
https://www.ncbi.nlm.nih.gov/pubmed/35106509
http://dx.doi.org/10.1016/j.xcrm.2021.100497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784794/
https://www.ncbi.nlm.nih.gov/pubmed/35106509
http://dx.doi.org/10.1016/j.xcrm.2021.100497

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