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Circulating Cell-Free Tumor DNA in Advanced Pancreatic Adenocarcinoma Identifies Patients With Worse Overall Survival

BACKGROUND: Plasma-based circulating cell-free tumor DNA (ctDNA) genomic profiling by next-generation sequencing (NGS)is an emerging diagnostic tool for pancreatic cancer (PC). The impact of detected genomic alterations and variant allele fraction (VAF) in tumor response to systemic treatments and o...

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Detalles Bibliográficos
Autores principales: Botrus, Gehan, Uson Junior, Pedro Luiz Serrano, Raman, Puneet, Kaufman, Adrienne E., Kosiorek, Heidi, Yin, Jun, Fu, Yu, Majeed, Umair, Sonbol, Mohamad Bassam, Ahn, Daniel H., Chang, Isabela W., Drusbosky, Leylah M., Dada, Hiba, Starr, Jason, Borad, Mitesh, Mody, Kabir, Bekaii-Saab, Tanios S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784799/
https://www.ncbi.nlm.nih.gov/pubmed/35083150
http://dx.doi.org/10.3389/fonc.2021.794009