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Dissecting Cellular Heterogeneity Based on Network Denoising of scRNA-seq Using Local Scaling Self-Diffusion

Identifying the phenotypes and interactions of various cells is the primary objective in cellular heterogeneity dissection. A key step of this methodology is to perform unsupervised clustering, which, however, often suffers challenges of the high level of noise, as well as redundant information. To...

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Detalles Bibliográficos
Autores principales: Duan, Xin, Wang, Wei, Tang, Minghui, Gao, Feng, Lin, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784844/
https://www.ncbi.nlm.nih.gov/pubmed/35082838
http://dx.doi.org/10.3389/fgene.2021.811043