Case Report: Partial Response Following Nivolumab Plus Docetaxel in a Patient With EGFR Exon 20 Deletion/Insertion (p.N771delinsGF) Mutant Lung Adenocarcinoma Transdifferentiated From Squamous Cell Carcinoma

The histological transformation from lung squamous cell carcinoma (LUSC) to lung adenocarcinoma (LUAD) and p. N771delinsGF mutations in EGFR exon 20 (ex20) are exceedingly rare in non–small cell lung carcinoma (NSCLC). EGFR ex20 mutations are insensitive to EGFR tyrosine kinase inhibitors in NSCLC....

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Detalles Bibliográficos
Autores principales: Zhu, Lingling, Liu, Yanyang, Gao, Honglin, Liu, Jiewei, Zhou, Qinghua, Luo, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784849/
https://www.ncbi.nlm.nih.gov/pubmed/35083213
http://dx.doi.org/10.3389/fcell.2021.755135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784849/
https://www.ncbi.nlm.nih.gov/pubmed/35083213
http://dx.doi.org/10.3389/fcell.2021.755135

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