Evaluation of Nonviral piggyBac and lentiviral Vector in Functions of CD19chimeric Antigen Receptor T Cells and Their Antitumor Activity for CD19(+) Tumor Cells

Nonviral transposon piggyBac (PB) and lentiviral (LV) vectors have been used to deliver chimeric antigen receptor (CAR) to T cells. To understand the differences in the effects of PB and LV on CAR T-cell functions, a CAR targeting CD19 was cloned into PB and LV vectors, and the resulting pbCAR and l...

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Detalles Bibliográficos
Autores principales: Lin, Zhicai, Liu, Xiangzhen, Liu, Tao, Gao, Haixia, Wang, Sitong, Zhu, Xingli, Rong, Lijie, Cheng, Jingbo, Cai, Zhigang, Xu, Fu, Tan, Xue, Lv, Linjie, Li, Zhong, Sun, Yan, Qian, Qijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784881/
https://www.ncbi.nlm.nih.gov/pubmed/35082789
http://dx.doi.org/10.3389/fimmu.2021.802705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784881/
https://www.ncbi.nlm.nih.gov/pubmed/35082789
http://dx.doi.org/10.3389/fimmu.2021.802705

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