Effects of Poly (ADP-ribose) Polymerase Inhibition on DNA Integrity and Gene Expression in Ovarian Follicular Cells in Mice with Endotoxemia

BACKGROUND: A mouse model of LPS-induced inflammation was used to investigate the effect of pharmacological inhibition of nuclear enzyme PARP-1 on oocyte maturation, apoptotic and necrotic death, as well as DNA integrity of follicular cells. Also, the relative expression of cumulus genes (HAS2, COX2...

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Detalles Bibliográficos
Autores principales: Kondratska, Olena, Grushka, Nataliya, Pavlovych, Svitlana, Krasutska, Nataliya, Tsyhankov, Serhii, Yanchii, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2022
Materias:
Full Length
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784896/
https://www.ncbi.nlm.nih.gov/pubmed/34826885
http://dx.doi.org/10.52547/ibj.26.1.44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784896/
https://www.ncbi.nlm.nih.gov/pubmed/34826885
http://dx.doi.org/10.52547/ibj.26.1.44

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