Cargando…

A Simplified Process for Purification and Refolding of Recombinant Human Interferon-α2b

BACKGROUND:  Interferon α-2b is a vital biotherapeutic produced through the recombinant DNA technology in E. coli. The recombinant IFN-α2b normally appears as intercellular IBs, which requires intensive refolding and purification steps. METHOD: Purification of IFN-α2b from solubilized IB was perform...

Descripción completa

Detalles Bibliográficos
Autores principales: Hezarjaribi, Nima, Fazeli, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784902/
https://www.ncbi.nlm.nih.gov/pubmed/34861751
http://dx.doi.org/10.52547/ibj.26.1.85