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A Simplified Process for Purification and Refolding of Recombinant Human Interferon-α2b
BACKGROUND: Interferon α-2b is a vital biotherapeutic produced through the recombinant DNA technology in E. coli. The recombinant IFN-α2b normally appears as intercellular IBs, which requires intensive refolding and purification steps. METHOD: Purification of IFN-α2b from solubilized IB was perform...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pasteur Institute of Iran
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784902/ https://www.ncbi.nlm.nih.gov/pubmed/34861751 http://dx.doi.org/10.52547/ibj.26.1.85 |