CCR1 and CCR5 mediate cancer-induced myelopoiesis and differentiation of myeloid cells in the tumor

BACKGROUND: Cancer-induced ‘emergency’ myelopoiesis plays a key role in tumor progression by inducing the accumulation of myeloid cells with a suppressive phenotype peripherally and in the tumor. Chemokine receptors (CCRs) and, in particular, CCR1, CCR2, CCR5, and CCR7 are emerging as key regulators...

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Detalles Bibliográficos
Autores principales: Zilio, Serena, Bicciato, Silvio, Weed, Donald, Serafini, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785210/
https://www.ncbi.nlm.nih.gov/pubmed/35064009
http://dx.doi.org/10.1136/jitc-2021-003131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785210/
https://www.ncbi.nlm.nih.gov/pubmed/35064009
http://dx.doi.org/10.1136/jitc-2021-003131

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