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CCR1 and CCR5 mediate cancer-induced myelopoiesis and differentiation of myeloid cells in the tumor
BACKGROUND: Cancer-induced ‘emergency’ myelopoiesis plays a key role in tumor progression by inducing the accumulation of myeloid cells with a suppressive phenotype peripherally and in the tumor. Chemokine receptors (CCRs) and, in particular, CCR1, CCR2, CCR5, and CCR7 are emerging as key regulators...
Autores principales: | Zilio, Serena, Bicciato, Silvio, Weed, Donald, Serafini, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785210/ https://www.ncbi.nlm.nih.gov/pubmed/35064009 http://dx.doi.org/10.1136/jitc-2021-003131 |
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