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Enhanced function of NR2C/2D-containing NMDA receptor in the nucleus accumbens contributes to peripheral nerve injury-induced neuropathic pain and depression in mice

N-methyl-d-aspartate receptors (NMDARs) dysfunction in the nucleus accumbens (NAc) participates in regulating many neurological and psychiatric disorders such as drug addiction, chronic pain, and depression. NMDARs are heterotetrameric complexes generally composed of two NR1 and two NR2 subunits (NR...

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Detalles Bibliográficos
Autores principales: Jing, Peng-Bo, Chen, Xiao-Hong, Lu, Huan-Jun, Gao, Yong-Jing, Wu, Xiao-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785348/
https://www.ncbi.nlm.nih.gov/pubmed/35057644
http://dx.doi.org/10.1177/17448069211053255