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Establishment of an Olfactory Region-specific Intranasal Delivery Technique in Mice to Target the Central Nervous System

We have recently developed a region-specific catheter-based intranasal application method in mice by using CT scan-based 3D cast models of the murine nose (DOI: 10.2376/0005-9366-17,102). This technique is able to specifically deliver drugs to the olfactory region or to the respiratory region only....

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Detalles Bibliográficos
Autores principales: Flamm, Johannes, Hartung, Sunniva, Gänger, Stella, Maigler, Frank, Pitzer, Claudia, Schindowski, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785418/
https://www.ncbi.nlm.nih.gov/pubmed/35082672
http://dx.doi.org/10.3389/fphar.2021.789780