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Proteomic profiling in cerebral amyloid angiopathy reveals an overlap with CADASIL highlighting accumulation of HTRA1 and its substrates

Cerebral amyloid angiopathy (CAA) is an age-related condition and a major cause of intracerebral hemorrhage and cognitive decline that shows close links with Alzheimer's disease (AD). CAA is characterized by the aggregation of amyloid-β (Aβ) peptides and formation of Aβ deposits in the brain va...

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Detalles Bibliográficos
Autores principales: Zellner, Andreas, Müller, Stephan A., Lindner, Barbara, Beaufort, Nathalie, Rozemuller, Annemieke J. M., Arzberger, Thomas, Gassen, Nils C., Lichtenthaler, Stefan F., Kuster, Bernhard, Haffner, Christof, Dichgans, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785498/
https://www.ncbi.nlm.nih.gov/pubmed/35074002
http://dx.doi.org/10.1186/s40478-021-01303-6