Identifying CCR5 coreceptor populations permissive for HIV-1 entry and productive infection: implications for in vivo studies

BACKGROUND: The chemokine receptor CCR5 is the major coreceptor for HIV-1 cell entry. We previously observed that not all CCR5 mAbs reduce HIV-1 infection, suggesting that only some CCR5 populations are permissive for HIV-1 entry. This study aims to better understand the relevant conformational stat...

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Detalles Bibliográficos
Autores principales: Weichseldorfer, Matthew, Tagaya, Yutaka, Reitz, Marvin, DeVico, Anthony L., Latinovic, Olga S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785515/
https://www.ncbi.nlm.nih.gov/pubmed/35073923
http://dx.doi.org/10.1186/s12967-022-03243-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785515/
https://www.ncbi.nlm.nih.gov/pubmed/35073923
http://dx.doi.org/10.1186/s12967-022-03243-8

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