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Disruption of hematopoiesis attenuates the osteogenic differentiation capacity of bone marrow stromal cells

BACKGROUND: The homeostasis of mesenchymal stem cells (MSCs) is modulated by both their own intracellular molecules and extracellular milieu signals. Hematopoiesis in the bone marrow is maintained by niche cells, including MSCs, and it is indispensable for life. The role of MSCs in maintaining hemat...

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Detalles Bibliográficos
Autores principales: Wang, Changzhen, Ning, Hongmei, Gao, Jiao, Xue, Teng, Zhao, Ming, Jiang, Xiaoxia, Zhu, Xiaoming, Guo, Ximin, Li, Hong, Wang, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785551/
https://www.ncbi.nlm.nih.gov/pubmed/35073981
http://dx.doi.org/10.1186/s13287-022-02708-3