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Cell maturation influences the ability of hESC-RPE to tolerate cellular stress

BACKGROUND: Transplantation of human pluripotent stem cell-derived retinal pigment epithelium (RPE) is an urgently needed treatment for the cure of degenerative diseases of the retina. The transplanted cells must tolerate cellular stress caused by various sources such as retinal inflammation and reg...

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Detalles Bibliográficos
Autores principales: Viheriälä, Taina, Hongisto, Heidi, Sorvari, Juhana, Skottman, Heli, Nymark, Soile, Ilmarinen, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785579/
https://www.ncbi.nlm.nih.gov/pubmed/35073969
http://dx.doi.org/10.1186/s13287-022-02712-7