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Estimating tuberculosis drug resistance amplification rates in high-burden settings

BACKGROUND: Antimicrobial resistance develops following the accrual of mutations in the bacterial genome, and may variably impact organism fitness and hence, transmission risk. Classical representation of tuberculosis (TB) dynamics using a single or two strain (DS/MDR-TB) model typically does not ca...

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Detalles Bibliográficos
Autores principales: Karmakar, Malancha, Ragonnet, Romain, Ascher, David B., Trauer, James M., Denholm, Justin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785585/
https://www.ncbi.nlm.nih.gov/pubmed/35073862
http://dx.doi.org/10.1186/s12879-022-07067-1