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HIV-2/SIV Vpx antagonises NF-κB activation by targeting p65

BACKGROUND: The NF-κB family of transcription factors and associated signalling pathways are abundant and ubiquitous in human immune responses. Activation of NF-κB transcription factors by viral pathogen-associated molecular patterns, such as viral RNA and DNA, is fundamental to anti-viral innate im...

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Detalles Bibliográficos
Autores principales: Fink, Douglas L., Cai, James, Whelan, Matthew V. X., Monit, Christopher, Maluquer de Motes, Carlos, Towers, Greg J., Sumner, Rebecca P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785589/
https://www.ncbi.nlm.nih.gov/pubmed/35073912
http://dx.doi.org/10.1186/s12977-021-00586-w