Loss of RPS27a expression regulates the cell cycle, apoptosis, and proliferation via the RPL11-MDM2-p53 pathway in lung adenocarcinoma cells

BACKGROUND: Depletion of certain ribosomal proteins induces p53 activation, which is mediated mainly by ribosomal protein L5 (RPL5) and/or ribosomal protein L11 (RPL11). Therefore, RPL5 and RPL11 may link RPs and p53 activation. Thus, this study aimed to explore whether RPs interact with RPL11 and r...

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Detalles Bibliográficos
Autores principales: Li, Hongyan, Zhang, Hong, Huang, Guomin, Bing, Zhitong, Xu, Duling, Liu, Jiadi, Luo, Hongtao, An, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785590/
https://www.ncbi.nlm.nih.gov/pubmed/35073964
http://dx.doi.org/10.1186/s13046-021-02230-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785590/
https://www.ncbi.nlm.nih.gov/pubmed/35073964
http://dx.doi.org/10.1186/s13046-021-02230-z

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