Pyruvate kinase M2 (PKM2) improve symptoms of post‐ischemic stroke depression by activating VEGF to mediate the MAPK/ERK pathway

PURPOSE: To evaluate and identify the effects and explore the mechanisms of pyruvate kinase M2 (PKM2) on stroke‐induced post stroke depression (PSD). METHODS: Rats were separated into six different groups, including sham + saline, Stroke + saline, PSD + saline, PSD + recombinant pyruvate kinase M2 (...

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Detalles Bibliográficos
Autores principales: Feng, Yun, Li, Xuebin, Wang, Jie, Huang, Xiaohua, Meng, Lanqing, Huang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785619/
https://www.ncbi.nlm.nih.gov/pubmed/34898024
http://dx.doi.org/10.1002/brb3.2450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785619/
https://www.ncbi.nlm.nih.gov/pubmed/34898024
http://dx.doi.org/10.1002/brb3.2450

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