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Pyruvate kinase M2 (PKM2) improve symptoms of post‐ischemic stroke depression by activating VEGF to mediate the MAPK/ERK pathway
PURPOSE: To evaluate and identify the effects and explore the mechanisms of pyruvate kinase M2 (PKM2) on stroke‐induced post stroke depression (PSD). METHODS: Rats were separated into six different groups, including sham + saline, Stroke + saline, PSD + saline, PSD + recombinant pyruvate kinase M2 (...
Autores principales: | Feng, Yun, Li, Xuebin, Wang, Jie, Huang, Xiaohua, Meng, Lanqing, Huang, Jianmin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785619/ https://www.ncbi.nlm.nih.gov/pubmed/34898024 http://dx.doi.org/10.1002/brb3.2450 |
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