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Pharmacological Inhibition of CETP (Cholesteryl Ester Transfer Protein) Increases HDL (High-Density Lipoprotein) That Contains ApoC3 and Other HDL Subspecies Associated With Higher Risk of Coronary Heart Disease

Plasma total HDL (high-density lipoprotein) is a heterogeneous mix of many protein-based subspecies whose functions and associations with coronary heart disease vary. We hypothesize that increasing HDL by CETP (cholesteryl ester transfer protein) inhibition failed to reduce cardiovascular disease ri...

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Detalles Bibliográficos
Autores principales: Furtado, Jeremy D., Ruotolo, Giacomo, Nicholls, Stephen J., Dullea, Robert, Carvajal-Gonzalez, Santos, Sacks, Frank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785774/
https://www.ncbi.nlm.nih.gov/pubmed/34937388
http://dx.doi.org/10.1161/ATVBAHA.121.317181