Statistically derived geometrical landscapes capture principles of decision-making dynamics during cell fate transitions

Fate decisions in developing tissues involve cells transitioning between discrete cell states, each defined by distinct gene expression profiles. The Waddington landscape, in which the development of a cell is viewed as a ball rolling through a valley filled terrain, is an appealing way to describe...

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Detalles Bibliográficos
Autores principales: Sáez, Meritxell, Blassberg, Robert, Camacho-Aguilar, Elena, Siggia, Eric D., Rand, David A., Briscoe, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785827/
https://www.ncbi.nlm.nih.gov/pubmed/34536382
http://dx.doi.org/10.1016/j.cels.2021.08.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785827/
https://www.ncbi.nlm.nih.gov/pubmed/34536382
http://dx.doi.org/10.1016/j.cels.2021.08.013

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