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Statistically derived geometrical landscapes capture principles of decision-making dynamics during cell fate transitions
Fate decisions in developing tissues involve cells transitioning between discrete cell states, each defined by distinct gene expression profiles. The Waddington landscape, in which the development of a cell is viewed as a ball rolling through a valley filled terrain, is an appealing way to describe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785827/ https://www.ncbi.nlm.nih.gov/pubmed/34536382 http://dx.doi.org/10.1016/j.cels.2021.08.013 |