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Back to the Future: Spatiotemporal Determinants of NK Cell Antitumor Function

NK cells play a crucial role in host protection during tumorigenesis. Throughout tumor development, however, NK cells become progressively dysfunctional through a combination of dynamic tissue-specific and systemic factors. While a number of immunosuppressive mechanisms present within the tumor micr...

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Detalles Bibliográficos
Autores principales: Li, Joey H., O’Sullivan, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785903/
https://www.ncbi.nlm.nih.gov/pubmed/35082797
http://dx.doi.org/10.3389/fimmu.2021.816658