Cargando…

A Novel Role for Cytochrome P450 Epoxygenase Metabolites in Septic Shock

This is the largest study describing the role of P450 epoxygenase metabolites in septic shock in humans and suggests a novel therapeutic target. OBJECTIVES: Oxylipins are oxidative breakdown products of cell membrane fatty acids. Animal models have demonstrated that oxylipins generated by the P450 e...

Descripción completa

Detalles Bibliográficos
Autores principales: Jones, Timothy N., Janani, Leila, Gordon, Anthony C., Al-Beidh, Farah, Antcliffe, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785925/
https://www.ncbi.nlm.nih.gov/pubmed/35083437
http://dx.doi.org/10.1097/CCE.0000000000000622