Cargando…
A Novel Role for Cytochrome P450 Epoxygenase Metabolites in Septic Shock
This is the largest study describing the role of P450 epoxygenase metabolites in septic shock in humans and suggests a novel therapeutic target. OBJECTIVES: Oxylipins are oxidative breakdown products of cell membrane fatty acids. Animal models have demonstrated that oxylipins generated by the P450 e...
Autores principales: | Jones, Timothy N., Janani, Leila, Gordon, Anthony C., Al-Beidh, Farah, Antcliffe, David B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785925/ https://www.ncbi.nlm.nih.gov/pubmed/35083437 http://dx.doi.org/10.1097/CCE.0000000000000622 |
Ejemplares similares
-
Opioids Activate Brain Analgesic Circuits Through Cytochrome P450/Epoxygenase Signaling
por: Conroy, Jennie L., et al.
Publicado: (2010) -
Extrahepatic cytochrome P450 epoxygenases: pathophysiology and clinical significance in human gastrointestinal cancers
por: Pidkovka, Nataliya, et al.
Publicado: (2021) -
The Cytochrome P450 Epoxygenase Pathway Regulates the Hepatic Inflammatory Response in Fatty Liver Disease
por: Schuck, Robert N., et al.
Publicado: (2014) -
Fenofibrate Inhibits Cytochrome P450 Epoxygenase 2C Activity to Suppress Pathological Ocular Angiogenesis
por: Gong, Yan, et al.
Publicado: (2016) -
CYP450 Epoxygenase Metabolites, Epoxyeicosatrienoic Acids, as Novel Anti-Inflammatory Mediators
por: Shi, Zeqi, et al.
Publicado: (2022)