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SARS-CoV-2 Spike Antagonizes Innate Antiviral Immunity by Targeting Interferon Regulatory Factor 3

Corona virus disease 2019 (COVID-19) pathogenesis is intimately linked to the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) and disease severity has been associated with compromised induction of type I interferon (IFN-I) cytokines which coordinate the innate immune response to virus...

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Detalles Bibliográficos
Autores principales: Freitas, Raul S., Crum, Tyler F., Parvatiyar, Kislay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785962/
https://www.ncbi.nlm.nih.gov/pubmed/35083167
http://dx.doi.org/10.3389/fcimb.2021.789462