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Repeated glucose spikes and insulin resistance synergistically deteriorate endothelial function and bardoxolone methyl ameliorates endothelial dysfunction

BACKGROUND: Both insulin resistance and postprandial glucose spikes are known for their potential to induce vascular endothelial dysfunction in individuals with metabolic syndrome. However, these factors are inextricable, and therefore, their relative contributions to inducing endothelial dysfunctio...

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Detalles Bibliográficos
Autores principales: Ogiso, Kazuma, Shayo, Sigfrid Casmir, Kawade, Shigeru, Hashiguchi, Hiroshi, Deguchi, Takahisa, Nishio, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786204/
https://www.ncbi.nlm.nih.gov/pubmed/35073378
http://dx.doi.org/10.1371/journal.pone.0263080