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Mutually exclusive mutation profiles define functionally related genes in muscle invasive bladder cancer

Muscle Invasive bladder cancer is known to have an abundance of mutations, particularly in DNA damage response and chromatin modification genes. The role of these mutations in the development and progression of the disease is not well understood. However, a mutually exclusive mutation pattern betwee...

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Detalles Bibliográficos
Autores principales: Sangster, Ami G., Gooding, Robert J., Garven, Andrew, Ghaedi, Hamid, Berman, David M., Davey, Scott K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786205/
https://www.ncbi.nlm.nih.gov/pubmed/35073341
http://dx.doi.org/10.1371/journal.pone.0259992