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SARS-CoV-2 Omicron spike mediated immune escape and tropism shift
The SARS-CoV-2 Omicron BA.1 variant emerged in late 2021 and is characterised by multiple spike mutations across all spike domains. Here we show that Omicron BA.1 has higher affinity for ACE2 compared to Delta, and confers very significant evasion of therapeutic monoclonal and vaccine-elicited polyc...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Journal Experts
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786230/ https://www.ncbi.nlm.nih.gov/pubmed/35075452 http://dx.doi.org/10.21203/rs.3.rs-1191837/v1 |