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Applications of Cryo-EM in small molecule and biologics drug design

Electron cryo-microscopy (cryo-EM) is a powerful technique for the structural characterization of biological macromolecules, enabling high-resolution analysis of targets once inaccessible to structural interrogation. In recent years, pharmaceutical companies have begun to utilize cryo-EM for structu...

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Detalles Bibliográficos
Autores principales: Lees, Joshua A., Dias, Joao M., Han, Seungil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786282/
https://www.ncbi.nlm.nih.gov/pubmed/34812853
http://dx.doi.org/10.1042/BST20210444