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PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling

Inflammasomes are protein complexes in the innate immune system that regulate the production of pro-inflammatory cytokines and inflammatory cell death. Inflammasome activation and subsequent cell death often occur within minutes to an hour, so the pathway must be dynamically controlled to prevent ex...

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Detalles Bibliográficos
Autores principales: McKee, Chloe M., Fischer, Fabian A., Bezbradica, Jelena S., Coll, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786285/
https://www.ncbi.nlm.nih.gov/pubmed/34854899
http://dx.doi.org/10.1042/BST20200987