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VDAC2 and the BCL-2 family of proteins

The BCL-2 protein family govern whether a cell dies or survives by controlling mitochondrial apoptosis. As dysregulation of mitochondrial apoptosis is a common feature of cancer cells, targeting protein–protein interactions within the BCL-2 protein family is a key strategy to seize control of apopto...

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Detalles Bibliográficos
Autores principales: Yuan, Zheng, Dewson, Grant, Czabotar, Peter E., Birkinshaw, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786305/
https://www.ncbi.nlm.nih.gov/pubmed/34913469
http://dx.doi.org/10.1042/BST20210753