New tools for automated cryo-EM single-particle analysis in RELION-4.0

We describe new tools for the processing of electron cryo-microscopy (cryo-EM) images in the fourth major release of the RELION software. In particular, we introduce VDAM, a variable-metric gradient descent algorithm with adaptive moments estimation, for image refinement; a convolutional neural netw...

Descripción completa

Detalles Bibliográficos
Autores principales: Kimanius, Dari, Dong, Liyi, Sharov, Grigory, Nakane, Takanori, Scheres, Sjors H. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786306/
https://www.ncbi.nlm.nih.gov/pubmed/34783343
http://dx.doi.org/10.1042/BCJ20210708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786306/
https://www.ncbi.nlm.nih.gov/pubmed/34783343
http://dx.doi.org/10.1042/BCJ20210708

Ejemplares similares