Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes

Cryogenic electron microscopy has become an essential tool for structure determination of biological macromolecules. In practice, the difficulty to reliably prepare samples with uniform ice thickness still represents a barrier for routine high-resolution imaging and limits the current throughput of...

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Detalles Bibliográficos
Autores principales: Huber, Stefan T, Sarajlic, Edin, Huijink, Roeland, Weis, Felix, Evers, Wiel H, Jakobi, Arjen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786315/
https://www.ncbi.nlm.nih.gov/pubmed/35060902
http://dx.doi.org/10.7554/eLife.72629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786315/
https://www.ncbi.nlm.nih.gov/pubmed/35060902
http://dx.doi.org/10.7554/eLife.72629

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