Local therapy with an engineered oncolytic adenovirus enables antitumor response in non-injected melanoma tumors in mice treated with aPD-1

Intratumoral immunotherapies are entering clinical use but concerns remain regarding their effects on non-injected tumors. Here, we studied the impact of local treatment with an adenovirus coding for TNFa and IL-2 on systemic antitumor response in animals receiving aPD-1 (anti-programmed cell death...

Descripción completa

Detalles Bibliográficos
Autores principales: Quixabeira, Dafne C. A., Cervera-Carrascon, Victor, Santos, Joao M., Clubb, James H.A., Kudling, Tatiana V., Basnet, Saru, Heiniö, Camilla, Grönberg-Vähä-Koskela, Susanna, Anttila, Marjukka, Havunen, Riikka, Kanerva, Anna, Hemminki, Akseli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786329/
https://www.ncbi.nlm.nih.gov/pubmed/35083096
http://dx.doi.org/10.1080/2162402X.2022.2028960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786329/
https://www.ncbi.nlm.nih.gov/pubmed/35083096
http://dx.doi.org/10.1080/2162402X.2022.2028960

Ejemplares similares