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Mitofusin-2 Restrains Hepatic Stellate Cells' Proliferation via PI3K/Akt Signaling Pathway and Inhibits Liver Fibrosis in Rats

The mitochondrial GTPase mitofusin-2 (MFN2) gene can suppress the cell cycle and regulate cell proliferation in a number of cell types. However, its function in hepatic fibrosis remains largely unexplored. We attempted to understand the mechanism of MFN2 in hepatic stellate cell (HSC) proliferation...

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Detalles Bibliográficos
Autores principales: Chen, Zhiping, Lin, Zeyu, Yu, Jiandong, Zhong, Haifeng, Zhuo, Xianhua, Jia, Changku, Wan, Yunle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786480/
https://www.ncbi.nlm.nih.gov/pubmed/35083025
http://dx.doi.org/10.1155/2022/6731335