Cargando…
Mitofusin-2 Restrains Hepatic Stellate Cells' Proliferation via PI3K/Akt Signaling Pathway and Inhibits Liver Fibrosis in Rats
The mitochondrial GTPase mitofusin-2 (MFN2) gene can suppress the cell cycle and regulate cell proliferation in a number of cell types. However, its function in hepatic fibrosis remains largely unexplored. We attempted to understand the mechanism of MFN2 in hepatic stellate cell (HSC) proliferation...
Autores principales: | Chen, Zhiping, Lin, Zeyu, Yu, Jiandong, Zhong, Haifeng, Zhuo, Xianhua, Jia, Changku, Wan, Yunle |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786480/ https://www.ncbi.nlm.nih.gov/pubmed/35083025 http://dx.doi.org/10.1155/2022/6731335 |
Ejemplares similares
-
INPP4B restrains cell proliferation and metastasis via regulation of the PI3K/AKT/SGK pathway
por: Chen, Ying, et al.
Publicado: (2018) -
MiR-195-5p suppresses the proliferation, migration, and invasion of gallbladder cancer cells by targeting FOSL1 and regulating the Wnt/β-catenin pathway
por: Zhu, Hongquan, et al.
Publicado: (2022) -
Primary Cilia Restrain PI3K-AKT Signaling to Orchestrate Human Decidualization
por: Li, Bo, et al.
Publicado: (2022) -
miR‐193a/b‐3p relieves hepatic fibrosis and restrains proliferation and activation of hepatic stellate cells
por: Ju, Baoling, et al.
Publicado: (2019) -
Thymosin-β4 inhibits proliferation and induces apoptosis of hepatic stellate cells through PI3K/AKT pathway
por: Zhu, Lili, et al.
Publicado: (2017)