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Dichotomy between the humoral and cellular responses elicited by mRNA and adenoviral vector vaccines against SARS-CoV-2

BACKGROUND: Protection from severe disease and hospitalization by SARS-CoV-2 vaccination has been amply demonstrated by real-world data. However, the rapidly evolving pandemic raises new concerns. One pertains efficacy of adenoviral vector-based vaccines, particularly the single-dose Ad26.COV2.S, re...

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Detalles Bibliográficos
Autores principales: Ukey, Rahul, Bruiners, Natalie, Mishra, Hridesh, Mishra, Pankaj K., McCloskey, Deborah, Onyuka, Alberta, Chen, Fei, Pinter, Abraham, Weiskopf, Daniela, Sette, Alessandro, Roy, Jason, Gaur, Sunanda, Gennaro, Maria Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786593/
https://www.ncbi.nlm.nih.gov/pubmed/35073931
http://dx.doi.org/10.1186/s12916-022-02252-0