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Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination

During the SARS-CoV-2 pandemic, novel and traditional vaccine strategies have been deployed globally. We investigated whether antibodies stimulated by mRNA vaccination (BNT162b2), including third-dose boosting, differ from those generated by infection or adenoviral (ChAdOx1-S and Gam-COVID-Vac) or i...

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Detalles Bibliográficos
Autores principales: Röltgen, Katharina, Nielsen, Sandra C.A., Silva, Oscar, Younes, Sheren F., Zaslavsky, Maxim, Costales, Cristina, Yang, Fan, Wirz, Oliver F., Solis, Daniel, Hoh, Ramona A., Wang, Aihui, Arunachalam, Prabhu S., Colburg, Deana, Zhao, Shuchun, Haraguchi, Emily, Lee, Alexandra S., Shah, Mihir M., Manohar, Monali, Chang, Iris, Gao, Fei, Mallajosyula, Vamsee, Li, Chunfeng, Liu, James, Shoura, Massa J., Sindher, Sayantani B., Parsons, Ella, Dashdorj, Naranjargal J., Dashdorj, Naranbaatar D., Monroe, Robert, Serrano, Geidy E., Beach, Thomas G., Chinthrajah, R. Sharon, Charville, Gregory W., Wilbur, James L., Wohlstadter, Jacob N., Davis, Mark M., Pulendran, Bali, Troxell, Megan L., Sigal, George B., Natkunam, Yasodha, Pinsky, Benjamin A., Nadeau, Kari C., Boyd, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786601/
https://www.ncbi.nlm.nih.gov/pubmed/35148837
http://dx.doi.org/10.1016/j.cell.2022.01.018