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HIV reservoir quantification using cross-subtype multiplex ddPCR

A major barrier to conducting HIV cure research in populations with the highest HIV burden is the lack of an accurate assay to quantify the replication-competent reservoir across the dominant global HIV-1 subtypes. Here, we modify a subtype B HIV-1 assay that quantifies both intact and defective pro...

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Detalles Bibliográficos
Autores principales: Cassidy, Noah A.J., Fish, Carolyn S., Levy, Claire N., Roychoudhury, Pavitra, Reeves, Daniel B., Hughes, Sean M., Schiffer, Joshua T., Benki-Nugent, Sarah, John-Stewart, Grace, Wamalwa, Dalton, Jerome, Keith R., Overbaugh, Julie, Hladik, Florian, Lehman, Dara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786636/
https://www.ncbi.nlm.nih.gov/pubmed/35106463
http://dx.doi.org/10.1016/j.isci.2021.103615