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Recapitulation of cell-like KRAS4b membrane dynamics on complex biomimetic membranes

Understanding the spatiotemporal distribution and dynamics of RAS on the plasma membrane (PM) is the key for elucidating the molecular mechanisms of the RAS signaling pathway. Single particle tracking (SPT) experiments show that in cells, KRAS diffuses in at least three interchanging states on the c...

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Detalles Bibliográficos
Autores principales: Shrestha, Rebika, Chen, De, Frank, Peter, Nissley, Dwight V., Turbyville, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786645/
https://www.ncbi.nlm.nih.gov/pubmed/35106460
http://dx.doi.org/10.1016/j.isci.2021.103608